KL044

KL044

AT32401

CAS 1801856-93-8

More details

1000 Items

$165.10

$165.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $107.95 Total: $539.75
110 $91.44 Total: $914.40
125 $77.47 Total: $1,936.75
150 $66.04 Total: $3,302.00
1100 $57.15 Total: $5,715.00

Overview

KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMPPKACREB pathway.

Chemical Properties

Molecular FormulaC21H14ClN3O
Molecular Weight359.81
CAS Numbers1801856-93-8
SolubilityDMSO
Purity98% by HPLC
SMILES CodeClc1cccc(C#N)c1NC(=O)Cn1c2ccccc2c2ccccc12

Storage and Handling

0C Short Term, -20C Long Term

References

Jae Wook Lee, et al. Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock. ChemMedChem. 2015 Sep;10[9] 1489-97.