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KL044 View larger

KL044

AT32401

CAS 1801856-93-8

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$127.00

$127.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $57.15 Total: $5,715.00
150 $66.04 Total: $3,302.00
125 $77.47 Total: $1,936.75
110 $91.44 Total: $914.40
15 $107.95 Total: $539.75

Data sheet

Molecular FormulaC21H14ClN3O
Molecular Weight359.81
CAS Numbers1801856-93-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeClc1cccc(C#N)c1NC(=O)Cn1c2ccccc2c2ccccc12
ReferencesJae Wook Lee, et al. Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock. ChemMedChem. 2015 Sep;10[9] 1489-97.

More info

KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMPPKACREB pathway.