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PH-002

AT16518

CAS 1311174-68-1

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.65 Total: $1,665.00
150 $19.24 Total: $962.00
125 $22.57 Total: $564.25
110 $26.64 Total: $266.40
15 $31.45 Total: $157.25

Data sheet

Molecular FormulaC27H33N5O4
Molecular Weight491.58
CAS Numbers1311174-68-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCn1nc(CC(=O)Nc2ccc(CN3CCN(CC3)C(=O)OC(C)(C)C)cc2)c2ccccc2c1=O
ReferencesBrodbeck J, et al. Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors. J Biol Chem. 2011 May 13;286[19] 17217-26.

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PH-002, an inhibitor targeting the intramolecular domain interaction of apolipoprotein (apo) E4 in neuronal cells, additionally enhances mitochondrial motility and promotes neurite outgrowth, thereby countering related impairments.