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Rare Chemicals
- Protein Control Ligand
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $69.70 | Total: $348.50 |
| 1 | 10 | $59.04 | Total: $590.40 |
| 1 | 25 | $50.02 | Total: $1,250.50 |
| 1 | 50 | $42.64 | Total: $2,132.00 |
| 1 | 100 | $36.90 | Total: $3,690.00 |
Data sheet
| Molecular Formula | C20H15F4N3O2 |
| Molecular Weight | 405.35 |
| CAS Numbers | 1802848-94-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | F[C@@H]1CCN(C1)C(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 |
| References | Patel MV, et al. Discovery of [R]-[3-fluoropyrrolidin-1-yl][6-[[5-[trifluoromethyl]pyridin-2-yl]oxy]quinolin-2-yl]methanone [ABBV-318] and analogs as small molecule Nav1.7 Nav1.8 blockers for the treatment of pain. Bioorg Med Chem. 2022 ; 63 116743. |
More info
ABBV-318 can be used as small molecule Nav1.7Nav1.8 blockers for the treatment of pain, with IC50 values of 2.8 ?M for hNav1.7 and 3.8 ?M for hNav1.8. ABBV-318 can be used to study pain-related disorders.