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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $69.70 | Total: $348.50 |
| 1 | 10 | $59.04 | Total: $590.40 |
| 1 | 25 | $50.02 | Total: $1,250.50 |
| 1 | 50 | $42.64 | Total: $2,132.00 |
| 1 | 100 | $36.90 | Total: $3,690.00 |
Overview
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of the sigma-1 receptor (?1 R, Ki = 3.88 nM) compared to the sigma-2 receptor (Ki = 1288 nM).
Chemical Properties
| Molecular Formula | C20H26ClN3O2 |
| Molecular Weight | 375.89 |
| CAS Numbers | 1639220-15-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc(cc1)-c1nc(C)c(Cl)c(OCCCN2CCCCC2)n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57[24] 10404-23.