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ICI-199441 hydrochloride
AOB6910
CAS No: 115199-84-3
Chemical Name: ICI199441 hydrochloride; 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C21H25Cl3N2O |
| Molecular Weight | 427.80 |
| CAS Numbers | 115199-84-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | ICI-199441 HCl; ICI 199441 HCl; ICI199441 HCl; ICI-199441 Hydrochloride; ICI 199441 Hydrochloride; ICI199441 Hydrochloride |
| IUPAC/Chemical Name | 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride |
| InChl Key | VFLWVWZSDBTGQJ-VEIFNGETSA-N |
| InChl Code | InChI=1S/C21H24Cl2N2O.ClH/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17;/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3;1H/t20-;/m1./s1 |
| SMILES Code | O=C(N(C)[C@@H](C1=CC=CC=C1)CN2CCCC2)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl |
| References | 1) Jacobs BA, Pando MM, Jennings E, Chavera TA, Clarke WP, Berg KA. Allosterism within δ Opioid-κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy. Mol Pharmacol. 2018 Apr;93(4):376-386. 2) Tsibulnikov SY, Maslov LN, Mukhomedzyanov AV, Krylatov AV, Tsibulnikova MR, Lishmanov YB. Prospects of Using of κ-Opioid Receptor Agonists U-50,488 and ICI 199,441 for Improving Heart Resistance to Ischemia/Reperfusion. Bull Exp Biol Med. 2015 Oct;159(6):718-21. |
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Highly potent κ agonist