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View larger AGPS-IN-2i
AOB17269
CAS: 2316782-88-2
Chemical Name: AGPS inhibitor 2i; 3-(2,6-Difluorophenyl)-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)butanamide
AOBIOUS launched this product in 2022
CITATIONS - Publications That Use AOBIOUS Product
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| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Data sheet
| Molecular Formula | C18H17F2N3O2 |
| Molecular Weight | 345.35 |
| CAS Numbers | 2316782-88-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | AGPS-IN-2i; AGPS IN 2i; AGPSIN2i; AGPS inhibitor 2i |
| IUPAC/Chemical Name | 3-(2,6-Difluorophenyl)-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)butanamide |
| InChl Key | VDLFVZUKOKPJRH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H17F2N3O2/c1-10(17-12(19)3-2-4-13(17)20)7-16(24)21-9-11-5-6-14-15(8-11)23-18(25)22-14/h2-6,8,10H,7,9H2,1H3,(H,21,24)(H2,22,23,25) |
| SMILES Code | CC(C1=C(F)C=CC=C1F)CC(NCC2=CC=C(C(N3)=C2)NC3=O)=O |
| References | 1) GiuliaStazi et al., Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells, European Journal of Medicinal Chemistry Volume 163, 1 February 2019, Pages 722-735 |
More info
Novel inhibitor of alkylglyceronephosphate synthase (AGPS), specifically impairing epithelial to mesenchymal transition (EMT) by modulating E-cadherin, Snail and MMP2 expression levels
