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NRX-252114 View larger

NRX-252114

AOB17866

CAS: N/A

 

Chemical Name: 2-(4-((2,6-Dichlorophenyl)thio)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonyl)isoindoline-4-carbonitrile

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$49.00

$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.05 Total: $2,205.00
150 $25.48 Total: $1,274.00
125 $29.89 Total: $747.25
110 $35.28 Total: $352.80
15 $41.65 Total: $208.25

Data sheet

Molecular FormulaC22H12Cl2F3N3O2S
Molecular Weight510.31
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC
IUPAC/Chemical Name2-(4-((2,6-Dichlorophenyl)thio)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonyl)isoindoline-4-carbonitrile
References1) Kyle R. Simonetta, et al., Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction, Nature Communications volume 10, Article number: 1402 (2019)

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Novel potent enhancer of the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP

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