Ubiquitin-Activating Enzyme

USP15-IN-1 View larger

USP15-IN-1

AT61575

CAS 2260826-16-0

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$109.00

$109.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $49.05 Total: $4,905.00
150 $56.68 Total: $2,834.00
125 $66.49 Total: $1,662.25
110 $78.48 Total: $784.80
15 $92.65 Total: $463.25

Data sheet

Molecular FormulaC22H23N3O3
Molecular Weight377.44
CAS Numbers2260826-16-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOCCNC(=O)c1ccc2[nH]c3CN(CCc3c2c1)C(=O)Cc1ccccc1
ReferencesChen Yihua, et al. The tetrahydro-beta-carboline micromolecular organic compound and its derivative and medical usage of a kind of hydroxyl substitution. CN108727370A

More info

USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 ?M) with high antiproliferative activity against non-small cell lung cancer and leukemia cells. As an interacting protein of cGAS, USP15 promotes cGAS to recognize DNA and activate downstream signaling pathways.