VC6TF - CiPSC Cocktail

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GW786460X (Repsox)

AOB1483

CAS No: 446859-33-2

 

Chemical Name: Repsox; 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine; ALK5 Inhibitor II

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$11.00

$11.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.95 Total: $495.00
150 $5.72 Total: $286.00
125 $6.71 Total: $167.75
110 $7.92 Total: $79.20
15 $9.35 Total: $46.75

Data sheet

Molecular FormulaC17H13N5
Molecular Weight287.3
CAS Numbers446859-33-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymE 616452; RepSox; SJN 2511
IUPAC/Chemical Name2-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine
InChl KeyLBPKYPYHDKKRFS-UHFFFAOYSA-N
InChl CodeInChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
SMILES CodeCC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1
References1) Gellibert et al. (2004), Identification of 1,5-Naphthyridine Derivatives as a Novel Series of Potent and Selective TGF-β Type I Receptor Inhibitors; J. Med. Chem. 47 44942) Ichida et al. (2009), A Small-molecule Inhibitor of TGF-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog; Cell Stem Cell 5 491

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Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β type I receptor (TGF-β R1, Alk5)

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