Votage-Gated Ion Channel Blockers

AqB011 View larger

AqB011

AOB0336

CAS No: 1021869-49-7

 

Chemical Name: 3-Butylamino-4-phenoxy-N-pyridin-3-ylmethyl-5-sulfamoyl-benzamide

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $16.65 Total: $1,665.00
50 $19.24 Total: $962.00
25 $22.57 Total: $564.25
10 $26.64 Total: $266.40
5 $31.45 Total: $157.25

Data sheet

Molecular FormulaC23H26N4O4S
Molecular Weight454.17
CAS Numbers1021869-49-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymAqB011; AqB-011; AqB 011
IUPAC/Chemical Name3-Butylamino-4-phenoxy-N-pyridin-3-ylmethyl-5-sulfamoyl-benzamide
InChl KeyFCBYGHMZVBDKMC-UHFFFAOYSA-N
InChl CodeInChI=1S/C23H26N4O4S/c1-2-3-12-26-20-13-18(23(28)27-16-17-8-7-11-25-15-17)14-21(32(24,29)30)22(20)31-19-9-5-4-6-10-19/h4-11,13-15,26H,2-3,12,16H2,1H3,(H,27,28)(H2,24,29,30)
SMILES CodeO=C(NCC1=CC=CN=C1)C2=CC(S(=O)(N)=O)=C(OC3=CC=CC=C3)C(NCCCC)=C2
References1) Kourghi M, De Ieso ML, Nourmohammadi S, Pei JV, Yool AJ. Identification of Loop D Domain Amino Acids in the Human Aquaporin-1 Channel Involved in Activation of the Ionic Conductance and Inhibition by AqB011. Front Chem. 2018 Apr 27;6:142.

2) Kourghi M, Pei JV, De Ieso ML, Nourmohammadi S, Chow PH, Yool AJ. Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life. Clin Exp Pharmacol Physiol. 2018 Apr;45(4):401-409.

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