AqB011

AqB011

AOB0336

CAS No: 1021869-49-7

 

Chemical Name: 3-Butylamino-4-phenoxy-N-pyridin-3-ylmethyl-5-sulfamoyl-benzamide

More details

962 Items

$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $31.45 Total: $157.25
110 $26.64 Total: $266.40
125 $22.57 Total: $564.25
150 $19.24 Total: $962.00
1100 $16.65 Total: $1,665.00

Overview

Selective blocker of the Aquaporin-1 ion channel conductance, slowing cancer cell migration

Chemical Properties

Molecular FormulaC23H26N4O4S
Molecular Weight454.17
CAS Numbers1021869-49-7
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name3-Butylamino-4-phenoxy-N-pyridin-3-ylmethyl-5-sulfamoyl-benzamide
InChl KeyFCBYGHMZVBDKMC-UHFFFAOYSA-N
InChl CodeInChI=1S/C23H26N4O4S/c1-2-3-12-26-20-13-18(23(28)27-16-17-8-7-11-25-15-17)14-21(32(24,29)30)22(20)31-19-9-5-4-6-10-19/h4-11,13-15,26H,2-3,12,16H2,1H3,(H,27,28)(H2,24,29,30)
SMILES CodeO=C(NCC1=CC=CN=C1)C2=CC(S(=O)(N)=O)=C(OC3=CC=CC=C3)C(NCCCC)=C2

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

AqB011; AqB-011; AqB 011

References

1) Kourghi M, De Ieso ML, Nourmohammadi S, Pei JV, Yool AJ. Identification of Loop D Domain Amino Acids in the Human Aquaporin-1 Channel Involved in Activation of the Ionic Conductance and Inhibition by AqB011. Front Chem. 2018 Apr 27;6:142.

2) Kourghi M, Pei JV, De Ieso ML, Nourmohammadi S, Chow PH, Yool AJ. Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life. Clin Exp Pharmacol Physiol. 2018 Apr;45(4):401-409.

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