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Overview
3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysishexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.
Chemical Properties
| Molecular Formula | C3H3BrO3 |
| Molecular Weight | 166.96 |
| CAS Numbers | 1113-59-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | OC(=O)C(=O)CBr |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Leng X , Peng J , Yu X , et al. 3-Bromopyruvic Acid, A Hexokinase II Inhibitor, is an Effective Antitumor Agent on the Hepatoma Cells in vitro and in vivo Findings[J]. Anti-Cancer Agents in Medicinal Chemistry [Formerly Current Medicinal Chemistry - Anti-Cancer Agents], 2014, 14[5] -.