ABT-510 acetate

ABT-510 acetate

AT24997

CAS 442526-87-6

More details

1000 Items

$59.80

$59.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $39.10 Total: $195.50
110 $33.12 Total: $331.20
125 $28.06 Total: $701.50
150 $23.92 Total: $1,196.00
1100 $20.70 Total: $2,070.00

Overview

ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer.ABT-510 acetate reduces angiogenesis and inflammatory responses in a mouse model of inflammatory bowel disease. ABT-510 acetate reduces angiogenesis and inflammation in mouse models of inflammatory bowel disease (IBD) and can be used in cancer research, particularly in epithelial ovarian cancer, as well as in inflammatory bowel disease (IBD).

Chemical Properties

Molecular FormulaC48H87N13O13
Molecular Weight1054.28
CAS Numbers442526-87-6
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(C)(O)=O.C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC(CNC(CN(C(C)=O)C)=O)=O)[C@H](C)C)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CCC)=O)[C@H](CC)C)=O)CCCNC(=N)N)(=O)N1[C@H](C(NCC)=O)CCC1

Storage and Handling

0C Short Term, -20C Long Term

References

Greenaway J, et al. ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Mol Cancer Ther. 2009;8[1] 64-74.