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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $253.30 | Total: $1,266.50 |
| 1 | 10 | $214.56 | Total: $2,145.60 |
| 1 | 25 | $181.78 | Total: $4,544.50 |
| 1 | 50 | $154.96 | Total: $7,748.00 |
| 1 | 100 | $134.10 | Total: $13,410.01 |
Overview
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.
Chemical Properties
| Molecular Formula | C19H21ClN2O2 |
| Molecular Weight | 344.84 |
| CAS Numbers | 314022-97-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(=O)(C1=C(OCC)C=CC=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Chopra A, et al. Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK30PLoS One. 2016 Apr 20;11[4] e0153818.