Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $85.00 | Total: $425.00 |
| 1 | 10 | $72.00 | Total: $720.00 |
| 1 | 25 | $61.00 | Total: $1,525.00 |
| 1 | 50 | $52.00 | Total: $2,600.00 |
| 1 | 100 | $45.00 | Total: $4,500.00 |
Overview
Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that often acts as a molecular glue. Mezigdomide has antimyeloma activity.
Chemical Properties
| Molecular Formula | C32H30FN5O4 |
| Molecular Weight | 567.61 |
| CAS Numbers | 2259648-80-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(CC1=CC=C(CN2CCN(CC2)C3=C(F)C=C(C#N)C=C3)C=C1)C4=C5C(C(=O)N(C5)[C@@H]6C(=O)NC(=O)CC6)=CC=C4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Nooka AK, et al. Mechanism of Action and Novel IMiD-Based Compounds and Combinations in Multiple Myeloma. Cancer J. 2019 JanFeb;25[1] 19-31.