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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $26.35 | Total: $131.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 100 | $13.95 | Total: $1,395.00 |
Overview
CFM 4 is a potent small molecule CARP-1APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosis, with an IC50 in the range of 10-15 ?M.CFM 4 inhibits the growth of drug-resistant human breast cancer cells.
Chemical Properties
| Molecular Formula | C22H16ClN3OS |
| Molecular Weight | 405.9 |
| CAS Numbers | 331458-02-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C2(C=3C(N1CC4=C(Cl)C=CC=C4)=CC=CC3)SC(=NN2)C5=CC=CC=C5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Puliyappadamba VT, et al. Antagonists of anaphase-promoting complex [APC]-2-cell cycle and apoptosis regulatory protein [CARP]-1 interaction are novel regulators of cell growth and apoptosis. J Biol Chem. 2011 Nov 4;286[44] 38000-38017.