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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $70.55 | Total: $352.75 |
| 1 | 10 | $59.76 | Total: $597.60 |
| 1 | 25 | $50.63 | Total: $1,265.75 |
| 1 | 50 | $43.16 | Total: $2,158.00 |
| 1 | 100 | $37.35 | Total: $3,735.00 |
Overview
GSK854 is a highly selective and potent inhibitor of troponin I interacting kinase (TNNI3K) that inhibits myocardial infarction-injured cellular pyroptosis and apoptosis in mice, which may limit oxidative stress, injury, and adverse remodeling in the ischemic heart.
Chemical Properties
| Molecular Formula | C18H19ClN6O4S2 |
| Molecular Weight | 482.96 |
| CAS Numbers | 1316059-00-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCS(=O)(=O)c1ccc(cc1Nc1cc(Nc2ccc(Cl)cn2)ncn1)S(=O)(=O)NC |
Storage and Handling
0C Short Term, -20C Long Term
References
Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase [TNNI3K] Inhibitors. J Med Chem. 2018;61[7] 3076-3088.