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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $142.80 | Total: $714.00 |
| 1 | 10 | $120.96 | Total: $1,209.60 |
| 1 | 25 | $102.48 | Total: $2,562.00 |
| 1 | 50 | $87.36 | Total: $4,368.00 |
| 1 | 100 | $75.60 | Total: $7,560.00 |
Overview
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mitochondrial mediation. Lucidenic acid B inhibits PMA-induced invasion of human hepatocellular carcinoma cells by inactivating the MAPKERK signaling pathway and decreasing the binding activity of NF-kappaB and AP-1. Lucidenic acid B had no effect on cell cycle and necrotic cells.
Chemical Properties
| Molecular Formula | C27H38O7 |
| Molecular Weight | 474.59 |
| CAS Numbers | 95311-95-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@]12C3=C([C@]4(C)[C@@](C[C@@H]3O)(C(C)(C)C(=O)CC4)[H])C(=O)[C@@H](O)[C@]1(C)[C@@]([C@@H](CCC(O)=O)C)(CC2=O)[H] |
Storage and Handling
0C Short Term, -20C Long Term
References
Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway.J Agric Food Chem. 2008 Jun 11;56[11] 3973-80.