Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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- Customized Screening Library
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- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $47.60 | Total: $238.00 |
| 1 | 10 | $40.32 | Total: $403.20 |
| 1 | 25 | $34.16 | Total: $854.00 |
| 1 | 50 | $29.12 | Total: $1,456.00 |
| 1 | 100 | $25.20 | Total: $2,520.00 |
Overview
Riviciclib hydrochloride (P276-00) is a novel inhibitor of CDK1, CDK4, and CDK9, with IC50 values of 79 nM, 63 nM, and 20 nM, respectively, currently in Phase 23.
Chemical Properties
| Molecular Formula | C21H20ClNO5 |
| Molecular Weight | 438.3 |
| CAS Numbers | 920113-03-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Joshi KS, et al. Mol Cancer Ther, 2007, 6[3], 918-925.