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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Overview
rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity against cancer cells. rac-CCT-250863 HCl can be used in combination with Pomalidomide to induce apoptosis and can be used in combined anti-cancer studies.
Chemical Properties
| Molecular Formula | C24H26ClF3N4O2S |
| Molecular Weight | 527 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC1=C(C=C(C=N1)C2=CC(CN(C)C)=CS2)C3=CC(OC(C=CC(F)(F)F)C)=C(C(N)=O)C=C3.Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Innocenti P, et al. Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2 structure-activity relationship, structural biology, and cellular activity. J Med Chem. 2012 ; 55[7] 3228-3241.