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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $32.30 | Total: $161.50 |
| 1 | 10 | $27.36 | Total: $273.60 |
| 1 | 25 | $23.18 | Total: $579.50 |
| 1 | 50 | $19.76 | Total: $988.00 |
| 1 | 100 | $17.10 | Total: $1,710.00 |
Overview
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK124 with Ki of 2 nM3 nM1 nM. It is less potent to CDK7 and GSK3??, while inactive to other kinases. Phase 1.
Chemical Properties
| Molecular Formula | C18H21F2N5O4S |
| Molecular Weight | 441.45 |
| CAS Numbers | 741713-40-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(CC2)S(C)(=O)=O)nc1N |
Storage and Handling
0C Short Term, -20C Long Term
References
Rodriguez A , et al. Mol Cancer Ther, 2006, 5[11], 2644-2658.