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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.
Chemical Properties
| Molecular Formula | C20H18N6O3 |
| Molecular Weight | 390.4 |
| CAS Numbers | 732983-37-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C=1N2C(C=C(N1)C3=CC(OC)=C(OC)C=C3)=NC=C2)C4=C(C(N)=O)C=CC=N4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yamamoto N, et al. The orally available spleen tyrosine kinase inhibitor 2-[7-[3,4-dimethoxyphenyl]-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide dihydrochloride [BAY 61-3606] blocks antigen-induced airway inflammation in rodents. J Pharmacol Exp Ther. 2003 Sep;306[3] 1174-81