Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
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- Antioxidant
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $92.65 | Total: $463.25 |
| 1 | 10 | $78.48 | Total: $784.80 |
| 1 | 25 | $66.49 | Total: $1,662.25 |
| 1 | 50 | $56.68 | Total: $2,834.00 |
| 1 | 100 | $49.05 | Total: $4,905.00 |
Overview
MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 ?M.
Chemical Properties
| Molecular Formula | C20H18N6O3 |
| Molecular Weight | 390.4 |
| CAS Numbers | 2271081-58-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc(Cn2cc(nn2)C(=O)NN=C2C(=O)Nc3c2cccc3C)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Aneja B, et al. Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis. Eur J Med Chem. 2019 Feb 1;163 840-852.