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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $85.85 | Total: $429.25 |
| 1 | 10 | $72.72 | Total: $727.20 |
| 1 | 25 | $61.61 | Total: $1,540.25 |
| 1 | 50 | $52.52 | Total: $2,626.00 |
| 1 | 100 | $45.45 | Total: $4,545.00 |
Overview
SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.
Chemical Properties
| Molecular Formula | C62H84N14O6 |
| Molecular Weight | 1121.42 |
| CAS Numbers | 957135-43-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@]12CC[C@H](N1C(=O)[C@H](CCCC2)NC(=O)[C@H](C)NC)C(=O)N[C@H](c1cn(CCCCc2ccc(CCCCn3cc(nn3)[C@@H](NC(=O)[C@@H]3CC[C@]4([H])CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N34)c3ccccc3)cc2)nn1)c1ccccc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Sun H, et al. Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP. J Am Chem Soc. 2007 Dec 12;129[49] 15279-94.