Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
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- Cancer Research
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- Metabolites
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- Customized Screening Library
- Ultra Pure Pharmacological Standard
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- Proteins and Antibodies
- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $61.20 | Total: $306.00 |
| 1 | 10 | $51.84 | Total: $518.40 |
| 1 | 25 | $43.92 | Total: $1,098.00 |
| 1 | 50 | $37.44 | Total: $1,872.00 |
| 1 | 100 | $32.40 | Total: $3,240.00 |
Overview
UC-514321 directly targets STAT35 and represses TET1 expression. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity.
Chemical Properties
| Molecular Formula | C26H35NO5 |
| Molecular Weight | 441.56 |
| CAS Numbers | 299420-83-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(N1CCOCC1)c1cc2OCOc2cc1O |
Storage and Handling
0C Short Term, -20C Long Term
References
Jiang X, et al. Targeted inhibition of STATTET1 axis as a therapeutic strategy for acute myeloid leukemia. Nat Commun. 2017 Dec 13;8[1] 2099.