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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $2,312.00 | Total: $11,560.00 |
| 1 | 10 | $1,958.40 | Total: $19,583.99 |
| 1 | 25 | $1,659.20 | Total: $41,480.02 |
| 1 | 50 | $1,414.40 | Total: $70,720.00 |
| 1 | 100 | $1,224.00 | Total: $122,400.05 |
Overview
KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormone-induced (Na+I- symporter) NIS expression and iodide ion uptake by modulating sodium iodide symporter protein expression and activity in thyroid cells. KT5823 induces apoptosis.
Chemical Properties
| Molecular Formula | C29H25N3O5 |
| Molecular Weight | 495.53 |
| CAS Numbers | 126643-37-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CN(C)C6=O)C=8C(N5[C@](O1)(C[C@@]2(C(OC)=O)OC)[H])=CC=CC8 |
Storage and Handling
0C Short Term, -20C Long Term
References
Gadbois DM, et al. Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells. Proc Natl Acad Sci U S A. 1992 Sep 15;89[18] 8626-30.