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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90? and yeast Hsp90 with IC50s of 3.2 and 6.6 ?M, respectively.CCT018159 inhibits key endothelial and tumor cell functions associated with invasion and angiogenesis. CCT018159 caused cellular inhibition associated with G1 phase block and induced apoptosis.
Chemical Properties
| Molecular Formula | C20H20N2O4 |
| Molecular Weight | 352.38 |
| CAS Numbers | 171009-07-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1=C(C(=NN1)C2=CC(CC)=C(O)C=C2O)C=3C=C4C(=CC3)OCCO4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Sharp SY, et al. In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors [published correction appears in Cancer Res. 2019 Jan 1;79[1] 287]. Cancer Res. 2007;67[5] 2206-2216.