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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
MMRi64 is a specific inhibitor of Mdm2-MdmX E3 ligase activity.MMRi64 potently induces p53 accumulation and apoptosis in the p53 pathway in leukemialymphoma cells, disrupts Mdm2-MdmX interactions, and downregulates Mdm2 and MdmX in leukemia cells.MMRi64 MMRi64 can be used in cancer research.
Chemical Properties
| Molecular Formula | C22H17Cl2N3O |
| Molecular Weight | 410.3 |
| CAS Numbers | 430458-66-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NC1=CC(C)=CC=N1)(C2=C(O)C3=C(C=C2)C=CC=N3)C4=C(Cl)C(Cl)=CC=C4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Wu W, et al. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemialymphoma cells. Cell Death Dis. 2015;6[12] e2035.