Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $286.45 | Total: $1,432.25 |
| 1 | 10 | $242.64 | Total: $2,426.40 |
| 1 | 25 | $205.57 | Total: $5,139.25 |
| 1 | 50 | $175.24 | Total: $8,762.00 |
| 1 | 100 | $151.65 | Total: $15,165.01 |
Overview
TJ08 is a 1,2,5-trisubstituted benzimidazole derivative with anticancer properties that effectively induces G1S phase blockade while promoting apoptotic effects in a variety of cancer cells.
Chemical Properties
| Molecular Formula | C22H16FN3O4 |
| Molecular Weight | 405.38 |
| CAS Numbers | 2924274-19-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C1=CC=C2C(N=C(N2CC3=CC=CC=C3)C4=CC([N+]([O-])=O)=C(F)C=C4)=C1)OC |
Storage and Handling
0C Short Term, -20C Long Term
References
Jagadeesha Gullahalli Swathantraiah, et al. Novel 1,2,5-Trisubstituted Benzimidazoles Potentiate Apoptosis by Mitochondrial Dysfunction in Panel of Cancer Cells. ACS Omega. 2022 Dec 6;7[50] 46955-46971.