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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $110.50 | Total: $552.50 |
| 1 | 10 | $93.60 | Total: $936.00 |
| 1 | 25 | $79.30 | Total: $1,982.50 |
| 1 | 50 | $67.60 | Total: $3,380.00 |
| 1 | 100 | $58.50 | Total: $5,850.00 |
Overview
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 ?M), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
Chemical Properties
| Molecular Formula | C22H29ClN4O3 |
| Molecular Weight | 432.94 |
| CAS Numbers | 1629268-00-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1(CC1)c1cc(NCC(=O)N2CCN(CC2)C2CN(C2)C(=O)C=C)c(O)cc1Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Lito P , Solomon M , Li L S , et al. Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism[J]. Science, 2016 science.aad6204.