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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
MY-1076 is a potent YAP inhibitor with antigastric cancer activity.MY-1076 dose-dependently induced G2M phase block, induced YAP degradation and apoptosis, and inhibited microtubule protein polymerization.MY-1076 inhibited the proliferation of MGC-803, SGC-7901, HCT-116, and KYSE450 cells.
Chemical Properties
| Molecular Formula | C29H33NO9 |
| Molecular Weight | 539.57 |
| CAS Numbers | 3008262-76-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC1=C(OC)C=CC(CN(C2=CC(OC)=C(OC)C(OC)=C2)C(C=CC3=CC(OC)=C(OC)C(OC)=C3)=O)=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Xiang-Jing Fu, et al. Design, synthesis and biological evaluation of N-benzylaryl cinnamide derivatives as tubulin polymerization inhibitors capable of promoting YAP degradation with potent anti-gastric cancer activities, European Journal of Medicinal Chemistry, Volume 262, 2023, 115883.