Categories
- PROTAC Linker
- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.05 | Total: $140.25 |
| 1 | 10 | $23.76 | Total: $237.60 |
| 1 | 25 | $20.13 | Total: $503.25 |
| 1 | 50 | $17.16 | Total: $858.00 |
| 1 | 100 | $14.85 | Total: $1,485.00 |
Overview
PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inflammatory activity, induces apoptosis, and arrests the cell cycle in the G2M phase.PARP-1-IN-3 may be useful for the study of cancer-related diseases. cancer-related diseases.
Chemical Properties
| Molecular Formula | C21H17BrN2O3 |
| Molecular Weight | 425.28 |
| CAS Numbers | 2976342-33-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(N)C=1C=CC=CC1OCC=2C=CC=C(C2)NC(=O)C3=CC=C(Br)C=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lu G, et, al. Discovery of novel benzamide derivatives bearing benzamidophenyl and phenylacetamidophenyl scaffolds as potential antitumor agents via targeting PARP-Eur J Med Chem. 2023 May 5;251 115243.