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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells
Chemical Properties
| Molecular Formula | C21H20Cl2N10O |
| Molecular Weight | 499.36 |
| CAS Numbers | 2387704-62-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cn1cc(cn1)-n1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(nc12)N1CCOCC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Quereda V, et al. Therapeutic Targeting of CDK12CDK13 in Triple-Negative Breast Cancer. Cancer Cell. 2019 Oct 8. pii S1535-6108[19]30424-6.