Categories
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- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $73.10 | Total: $365.50 |
| 1 | 10 | $61.92 | Total: $619.20 |
| 1 | 25 | $52.46 | Total: $1,311.50 |
| 1 | 50 | $44.72 | Total: $2,236.00 |
| 1 | 100 | $38.70 | Total: $3,870.00 |
Overview
STM2457 is an inhibitor of the RNA methyltransferase METTL3 (IC50=16.9 nM) with selective and oral activity.STM2457 can be used in acute myeloid leukemia (AML) studies.
Chemical Properties
| Molecular Formula | C25H28N6O2 |
| Molecular Weight | 444.53 |
| CAS Numbers | 2499663-01-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yankova E, et al. Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature. 2021 May;593[7860] 597-601.