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Overview
Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA. Sodium Oxamate has antitumor activity and induces cell cycle arrest and apoptosis.
Chemical Properties
| Molecular Formula | C2H2NNaO3 |
| Molecular Weight | 111.03 |
| CAS Numbers | 565-73-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [Na+].NC(=O)C([O-])=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Qiao T, et al. Inhibition of LDH-A by Oxamate Enhances the Efficacy of Anti-PD-1 Treatment in an NSCLC Humanized Mouse Model. Front Oncol. 2021 Mar 30;11 632364.