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Overview
Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative with affinity for elastin-containing connective tissues and formulated as a prodrug. Sulfasalazine induces iron death and inhibits NF-?B, TGF-? and COX-2.
Chemical Properties
| Molecular Formula | C18H14N4O5S |
| Molecular Weight | 398.39 |
| CAS Numbers | 599-79-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | OC(=O)C1=CC(=CC=C1O)N=NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=N1 |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Gadangi P, et al. J Immunol,1996, 156[5], 1937-1941.
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