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Overview
Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.
Chemical Properties
| Molecular Formula | C27H30O6 |
| Molecular Weight | 450.52 |
| CAS Numbers | 64506-49-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(CC(O)=O)C1=C(C(C=CC2=CC=C(OCC=C(C)C)C=C2)=O)C=CC(OCC=C(C)C)=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Onda K, et al. Sofalcone upregulates the nuclear factor [erythroid-derived 2]-like 2heme oxygenase-1 pathway, reduces soluble fms-like tyrosine kinase-1, and quenches endothelial dysfunction potential therapeutic for preeclampsia. Hypertension. 2015 Apr;65[4] 855-62.