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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin?1 is a potent and selective PIKfyve inhibitor and inhibits late?stage autophagy by impairing lysosomal maturation
Chemical Properties
| Molecular Formula | C26H24IN7O |
| Molecular Weight | 577.42 |
| CAS Numbers | 351986-85-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Ic1cccc(C=NNc2nc(nc(n2)N2CCOCC2)N(c2ccccc2)c2ccccc2)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yingying Lu, et al. Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A. Autophagy