Lys-[Des-Arg9]Bradykinin,TFA

Lys-[Des-Arg9]Bradykinin,TFA

ATP1918L

1000 Items

$87.10

$87.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $56.95 Total: $284.75
110 $48.24 Total: $482.40
125 $40.87 Total: $1,021.75
150 $34.84 Total: $1,742.00
1100 $30.15 Total: $3,015.00

Overview

Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin.

Chemical Properties

Molecular FormulaC54H75F6N13O15
Molecular Weight1260.24
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(N1[C@H](C(NCC(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N3[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CCC3)=O)CO)=O)=O)=O)CCC1)[C@H]5N(C([C@@H](NC([C@H](CCCCN)N)=O)CCCNC(N)=N)=O)CCC5.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O

Storage and Handling

0C Short Term, -20C Long Term

References

Drapeau et al [1991] Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins. J.Pharmacol.Exp.Ther. 259 997 PMID