Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
![Sar-[D-Phe8]-des-Arg9-Bradykinin acetate](https://img.aobious.com/img/p/5/1/9/1/2/51912-large_default.webp "Sar-[D-Phe8]-des-Arg9-Bradykinin acetate")
![Sar-[D-Phe8]-des-Arg9-Bradykinin acetate](https://img.aobious.com/img/p/5/1/9/1/2/51912.jpg "Sar-[D-Phe8]-des-Arg9-Bradykinin acetate")
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $222.70 | Total: $1,113.50 |
| 1 | 10 | $188.64 | Total: $1,886.40 |
| 1 | 25 | $159.82 | Total: $3,995.50 |
| 1 | 50 | $136.24 | Total: $6,812.00 |
| 1 | 100 | $117.90 | Total: $11,790.01 |
Overview
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic activity in vivo.
Chemical Properties
| Molecular Formula | C49H70N12O13 |
| Molecular Weight | 1035.15 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@H](CC5=CC=CC=C5)C(=O)O.CC(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Drapeau et al [1991] Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins. J.Pharmacol.Exp.Ther. 259 997 PMID