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Overview
Diltiazem hydrochloride (RG 83606 HCl) is a benzothiazepine calcium channel blocking agent with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.
Chemical Properties
| Molecular Formula | C22H27ClN2O4S |
| Molecular Weight | 450.98 |
| CAS Numbers | 33286-22-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | Cl.COc1ccc(cc1)[C@@H]1Sc2ccccc2N(CCN(C)C)C(=O)[C@@H]1OC(C)=O |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Kraus RL, et al. Molecular mechanism of diltiazem interaction with L-type Ca2+ channels. J Biol Chem. 1998 Oct 16;273[42] 27205-12.