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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $23.80 | Total: $119.00 |
| 1 | 10 | $20.16 | Total: $201.60 |
| 1 | 25 | $17.08 | Total: $427.00 |
| 1 | 50 | $14.56 | Total: $728.00 |
| 1 | 100 | $12.60 | Total: $1,260.00 |
Overview
YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 has efficient protective effects on neurons and kidneys.
Chemical Properties
| Molecular Formula | C26H22FN3O3 |
| Molecular Weight | 443.47 |
| CAS Numbers | 838819-70-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Nc1cccc(CNC(=O)c2ccc(Oc3ccc(OCc4cccc(F)c4)cc3)nc2)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Takahiro Iwamoto, et al. YM-244769, a Novel Na + Ca 2+ Exchange Inhibitor That Preferentially Inhibits NCX3, Efficiently Protects Against hypoxiareoxygenation-induced SH-SY5Y Neuronal Cell Damage. Mol Pharmacol. 2006 Dec;70[6] 2075-83.