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Oxaliplatin
AOB6189
CAS: 61825-94-3
Chemical Name: Eloxatin; Foloxatine; Eloxatine; [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioata(2--)-O,O']platinum
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
Anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA
Chemical Properties
| Molecular Formula | C8H14N2O4Pt |
| Molecular Weight | 397.29 |
| CAS Numbers | 61825-94-3 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | [(1R,2R)-cyclohexane-1,2-diamine](ethanedioato-O,O')platinum(II) |
| InChl Key | ZROHGHOFXNOHSO-UHFFFAOYSA-L |
| InChl Code | InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2 |
| SMILES Code | O=C1[O-][Pt+2]2([O-]C1=O)[NH2]C3CCCCC3[NH2]2 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
diaminocyclohexane oxalatoplatinum; oxalatoplatin; oxalatoplatinum; US brand name: Eloxatin Foreign brand names: Dacotin; Dacplat; Eloxatine; Abbreviations: 1OHP; LOHP; Code names: JM83; RP54780; SR96669.
References
1) Ye F, Liu Z, Tan A, Liao M, Mo Z, Yang X. XRCC1 and GSTP1 polymorphisms and prognosis of oxaliplatin-based chemotherapy in colorectal cancer: a meta-analysis. Cancer Chemother Pharmacol. 2013 Mar;71(3):733-40. doi: 10.1007/s00280-012-2067-8. Epub 2013 Jan 9. Review. PubMed PMID: 23299794.
2) Leon-Ferre RA, Abu Hejleh TB, Halfdanarson TR. Extravasation of oxaliplatin into the mediastinum: a case report and review of the literature. Clin Adv Hematol Oncol. 2012 Aug;10(8):546-8. Review. PubMed PMID: 23073056.