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BT-11 (Omilancor) dihydrochloride
AOB16934
CAS: 1912399-75-7
Chemical Name: Piperazine-1,4-diylbis((6-(1H-benzo[d]imidazol-2-yl)pyridin-2-yl)methanone) dihydrochloride
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity (mg or Unit) | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|
| 5 | $17.85 | Total: $89.25 |
| 10 | $15.12 | Total: $151.20 |
| 25 | $12.81 | Total: $320.25 |
| 50 | $10.92 | Total: $546.00 |
| 100 | $9.45 | Total: $945.00 |
Overview
Novel Activator of Lanthionine synthetase C-like 2 (LANCL2), Ameliorating Inflammatory Bowel Disease by Enhancing Regulatory T Cell Responses in the Gut, Supporting Regulatory T Cell Stability Through Immunometabolic Mechanisms
Chemical Properties
| Molecular Formula | C30H26Cl2N8O2 |
| Molecular Weight | 601.49 |
| CAS Numbers | 1912399-75-7 |
| Solubility | DMSO: ≥ 30 mg/mL |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | Piperazine-1,4-diylbis((6-(1H-benzo[d]imidazol-2-yl)pyridin-2-yl)methanone) dihydrochloride |
| SMILES Code | O=C(N1CCN(C(C2=NC(C3=NC4=CC=CC=C4N3)=CC=C2)=O)CC1)C5=NC(C6=NC7=CC=CC=C7N6)=CC=C5 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Omilancor; B11
References
1) Adria Carbo et al., An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease, J Med Chem. 2016 Nov 23;59(22):10113-10126. doi: 10.1021/acs.jmedchem.6b00412. Epub 2016 Nov 15.