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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $56.95 | Total: $284.75 |
| 1 | 10 | $48.24 | Total: $482.40 |
| 1 | 25 | $40.87 | Total: $1,021.75 |
| 1 | 50 | $34.84 | Total: $1,742.00 |
| 1 | 100 | $30.15 | Total: $3,015.00 |
Overview
CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.
Chemical Properties
| Molecular Formula | C33H31Cl2F3N6O3S2 |
| Molecular Weight | 751.67 |
| CAS Numbers | 1429239-98-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC(F)(F)c1ccc(cc1)C#Cc1ccc(s1)-c1c(CNS(=O)(=O)N2CCCC2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Chang C P , Wu C H , Song J S , et al. Discovery of 1-[2,4-dichlorophenyl]-N-[piperidin-1-yl]-4-[[pyrrolidine-1-sulfonamido]methyl]-5-[5-[[4-[trifluoromethyl]phenyl]ethynyl]thiophene-2-yl]-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice.[J]. Journal of Medicinal Chemistry, 2013, 56[24] 9920.