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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $40.80 | Total: $204.00 |
| 1 | 10 | $34.56 | Total: $345.60 |
| 1 | 25 | $29.28 | Total: $732.00 |
| 1 | 50 | $24.96 | Total: $1,248.00 |
| 1 | 100 | $21.60 | Total: $2,160.00 |
Overview
Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).
Chemical Properties
| Molecular Formula | C19H21ClFN3O4S |
| Molecular Weight | 441.9 |
| CAS Numbers | 954126-98-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@H]1CCCNC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Miller BE, et al. The pharmacokinetics and pharmacodynamics of danirixin [GSK1325756]--a selective CXCR2 antagonist --in healthy adult subjects. BMC Pharmacol Toxicol. 2015 Jun 20;16 18.