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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Overview
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
Chemical Properties
| Molecular Formula | C17H17Cl2FN4O4S |
| Molecular Weight | 463.31 |
| CAS Numbers | 688763-64-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | S(=O)(=O)(C1=C(O)C(NC(NC2=C(Cl)C(F)=CC=C2)=O)=CC=C1Cl)N3CCNCC3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lazaar AL, et al. SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. Br J Clin Pharmacol. 2011 Aug;72[2] 282-93.