ZK 756326

ZK 756326

AT3360

CAS 874911-96-3

More details

1000 Items

$44.20

$44.20 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $28.90 Total: $144.50
110 $24.48 Total: $244.80
125 $20.74 Total: $518.50
150 $17.68 Total: $884.00
1100 $15.30 Total: $1,530.00

Overview

ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 ?M, in human; 2.6 ?M, in mouse). Displays no activity at CCR45 and CXCR34 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at ?2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.

Chemical Properties

Molecular FormulaC21H28N2O3
Molecular Weight356.46
CAS Numbers874911-96-3
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cl.OCCOCCN1CCN(Cc2cccc(Oc3ccccc3)c2)CC1

Storage and Handling

0C Short Term, -20C Long Term

References

Haskell Ca, et al. Mol Pharmacol. 2006, 69[1] 309-16.