Isodeoxycholic Acid

Isodeoxycholic Acid

AT36585

CAS 566-17-6

More details

1000 Items

$61.10

$61.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $39.95 Total: $199.75
110 $33.84 Total: $338.40
125 $28.67 Total: $716.75
150 $24.44 Total: $1,222.00
1100 $21.15 Total: $2,115.00

Overview

Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less active than DCA in inhibiting growth in a panel of seven gut commensal bacteria species. Isodeoxycholic Acid(0.1%) inhibits spore germination induced by taurocholic acid in several C. difficile strains, as well as decreases the cytotoxicity of C. difficile culture supernatants to Vero cells. Plasma levels of isodeoxycholic acid are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.

Chemical Properties

Molecular FormulaC24H40O4
Molecular Weight392.57
CAS Numbers566-17-6
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@]12[C@@]3([C@]([C@]4([C@](C)([C@@H](O)C3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@H](O)C[C@@]1(CCCC2)[H])[H])[H]

Storage and Handling

0C Short Term, -20C Long Term

References

Takei H, et al. Characterization of long-chain fatty acid-linked bile acids a major conjugation form of 3?-hydroxy bile acids in feces. J Lipid Res. 2022;63[10] 100275.