C3a Receptor Agonist

C3a Receptor Agonist

AT38287

CAS 944997-60-8

More details

1000 Items

$98.80

$98.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $64.60 Total: $323.00
110 $54.72 Total: $547.20
125 $46.36 Total: $1,159.00
150 $39.52 Total: $1,976.00
1100 $34.20 Total: $3,420.00

Overview

C3a Receptor Agonist (C3a receptor agonist 1) binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from being mobilized in a model of intestinal ischemia-reperfusion injury. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. C3a stimulates differentiation of neural progenitor cells in vitro.

Chemical Properties

Molecular FormulaC27H35N3O2
Molecular Weight433.59
CAS Numbers944997-60-8
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(CCc1cccnc1)N1CCC(CC1)NC(=O)C(C1CCCCC1)c1ccccc1

Storage and Handling

0C Short Term, -20C Long Term

References

Klos, A., Wende, E., Wareham, K.J., et al. International union of basic and clinical pharmacology. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol. Rev. 65[1], 500-543 [2013].