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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $112.20 | Total: $561.00 |
| 1 | 10 | $95.04 | Total: $950.40 |
| 1 | 25 | $80.52 | Total: $2,013.00 |
| 1 | 50 | $68.64 | Total: $3,432.00 |
| 1 | 100 | $59.40 | Total: $5,940.00 |
Overview
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.
Chemical Properties
| Molecular Formula | C25H31ClN2O4 |
| Molecular Weight | 458.98 |
| CAS Numbers | 1646321-63-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Dimitrios C Mastellos, et al. Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria. Semin Hematol. 2018 Jul;55[3] 167-175.